Experience healing with 
fast-acting ketamine-based therapy

Reduce symptoms of depression and anxiety with
minimal side effects

Rapid depression relief

Scientifically proven

Covered by major insurances

Experience healing
with fast-acting
ketamine-based therapy

Reduce symptoms of depression and
anxiety with minimal side effects

Rapid depression relief

Scientifically proven

Covered by major insurances

WHAT IS NASAL ESKETAMINE?

The change you've been
looking for

Unlike oral antidepressants, which can take several weeks, even months, to work,
Nasal Esketamine patients can feel better within days.

WHAT IS NASAL ESKETAMINE?

The change you've
been looking for

Unlike oral antidepressants, which
can take several weeks to months to
work, Nasal Esketamine patients can
feel better within days.

THE SCIENCE

Science-Backed, Safe
and Effective

Esketamine nasal spray helps correct abnormal brain activity in patients using a mechanism of action that is completely different from classic antidepressants, providing relief from depressive symptoms.

THE SCIENCE

Science-Backed, Safe, and Effective

Esketamine nasal spray helps restore neurotransmitter connections and
improve synaptic plasticity,
providing relief from depressive
symptoms.

OUR PROCESS

Getting Started

Schedule a FREE consultation 


You will meet with an expert member of our care team where they will provide you with a FREE mental health evaluation

Pre-Assessment


A licensed depression specialist will design a personalized treatment plan just for you 

Treatment

Next, you'll begin your treatment & feel
improvement within days

OUR PROCESS

Getting Started

  • NO COST CONSULT

    Mental health evaluation with an expert member of our care team

  • PRE-ASSESSMENT

    Licensed depression specialist designs a personalized treatment plan

  • TREATMENT

    Begin treatment & feel improvement within days

Get A Free Consult

INSURANCE COVERAGE

We handle all the paperwork

Our care team does all the work for you when it comes to insurance:
phone calls, emails, paperwork and even walking you through your
standard insurance plan criteria.

Covered by major insurance companies

and many more!

INSURANCE COVERAGE

We handle all the
paperwork

Our care team does all the work for
you when it comes to insurance:
phone calls, emails, paperwork and
even walking you through your
standard insurance plan criteria.

Covered by major insurance
companies

and many more!

HOW IT WORKS

Typical Treatment Plan

2 treatments a
week for 4 Weeks

1 treatment a week
for 4 weeks

1 treatment every
1-2 weeks

Begin My Journey

HOW IT WORKS

Typical
Treatment Plan

2 treatments a week for 4 Weeks

1 treatment a week for 4 weeks

1 treatment every 1-2 weeks

TESTIMONIALS

Real Lives Changed

Real Lives Changed 

TESTIMONIALS

ESKETAMINE SPRAY VS. IV KETAMINE

There's Only One 
FDA-Approved For Depression

Esketamine Nasal Spray

IV Ketamine Options

Covered by major insurance companies

FDA Approved for the treatment of depression 

Nasal spray under medical supervision

Well-established dosing and treatment frequency 

Not covered by
many insurances

Not FDA Approved for the treatment of depression 

Needle injections, no
confirmed supervision

No consensus on dosing and treatment frequency 

Learn More

ESKETAMINE SPRAY VS. IV KETAMINE

There's Only One 
FDA-Approved For
Depression

Esketamine
Nasal Spray

IV Ketamine
Options

Covered by major insurance companies 

FDA Approved for the treatment of depression

Nasal spray under medical supervision

Well-established dosing and treatment frequency

Not covered by many insurances

Not FDA Approved for the treatment of depression 

Needle injections, no confirmed supervision

No consensus on dosing and treatment frequency

Fast-Acting Depression
Drug, Newly Approved,
Could Help Millions

You Can Feel Better

Start treatment today and feel relief as
soon as tomorrow

Begin My Journey

You Can Feel Better

Start treatment today and feel relief
as soon as tomorrow

© 2024 Greenbrook TMS. All Rights Reserved

© 2022 Greenbrook TMS. All Rights Reserved

Frequently Asked Questions

Can you take esketamine nasal spray while staying on medication?

Yes. You have to be on an antidepressant medication to receive nasal esketamine spray.

Am I a candidate for esketamine nasal spray?

Esketamine nasal spray is FDA approved for two indications:

  • Treatment-resistant depression (patients who have tried previous oral antidepressants with unsatisfactory results)
  • Depressive symptoms in adults with major depressive disorder with suicidal thoughts or actions

You shouldn't take esketamine nasal spray if you have:

  • Uncontrolled hypertension
  • History of strokes or brain bleeds
  • Abnormal blood vessels at risk of bleeding, such as aneurysms or ateriorvenous malformations (AVMs)
  • Sensitivity to eketamine

During your free consultation, our team will help you decide if ketamine-based depression treatment is right for you.


How long is a round of esketamine nasal spray treatment?

A typical round of esketamine nasal spray treatment consists of 24-26 sessions in four phases:

  • Phase 1: 2 treatments a week for 4 weeks
  • Phase 2: 1 treatment a week for 4 weeks
  • Phase 3: 1 treatment every 1-2 weeks
  • Phase 4: Maintenance program consisting of 12-14 additional treatments

Before coming to each appointment, be sure you avoid eating anything for two hours. You should also avoid large amounts of fluid for 30 minutes before an appointment.

Each session takes place at a private, spa-like Greenbrook center. Once you arrive, you'll sit in a chair and self-administer the nasal spray. Your blood pressure is checked at the start of the session, 40 mins into treatment, and prior to leaving the Greenbrook center.

You have to stay in the center for no less than two hours. Make sure you have someone to drive you home.


Does esketamine nasal spray help treat anxiety?

No. Esketamine nasal spray is FDA approved for two indications:

  • Treatment-resistant depression (patients who have tried previous oral antidepressants with unsatisfactory results)
  • Major depressive disorder with acute harmful behaviors

Is esketamine nasal spray covered by insurance?

Yes! It's covered by many major insurance companies. Greenbrook's Care Team will handle all the insurance for you. On average, an insurance company will cover about 28 treatment sessions.

Frequently Asked
Questions

Phase 1 

Phase 2 

Phase 3